I am hanging in there....

ALS-linked gene causes disease by changing genetic material's shape

This image shows nucleolin (green) scattered throughout the nucleus (blue) in a motor neuron obtained from induced pluripotent stem cells generated from the skin biopsy of an amyotrophic lateral sclerosis patient. Credit: Jiou Wang, Ph.D., Johns Hopkins University.

Johns Hopkins researchers say they have found one way that a recently discovered genetic mutation might cause two nasty nervous system diseases. While the affected gene may build up toxic RNA and not make enough protein, the researchers report, the root of the problem seems to be snarls of defective genetic material created at the mutation site.

This is our writing group celebrating our 8th anniversary. It is amazing that we have stayed together 8 years. We really enjoy each others company and discussions.